August, 2010
Two mouse experiments have found that the drug carvedilol, prescribed for the treatment of hypertension, significantly improved synaptic transmission in Alzheimer's disease-type brains, and at a behavioral level significantly improved learning and memory.
Reference:
[1691]
(Submitted). Carvedilol as a potential novel agent for the treatment of Alzheimer's disease.
Neurobiology of Aging. In Press, Corrected Proof,
Arrieta-Cruz, I. et al. 2010. Carvedilol Reestablishes Long-Term Potentiation in a Mouse Model of Alzheimer’s Disease. Journal of Alzheimer's Disease, 21 (2), in press.