Type of fat, not amount of fat, linked to cognitive decline in old age

June, 2012

A large four-year study of older women has found high amounts of saturated fat were associated with greater cognitive decline, while higher amounts of monounsaturated fat were associated with better performance.

Data from the Women's Health Study, involving 6,183 older women (65+), has found that it isn’t the amount of fat but the type of fat that is associated with cognitive decline. The women were given three cognitive function tests at two-yearly intervals, and filled out very detailed food frequency surveys at the beginning of the study.

Women who consumed the highest amounts of saturated fat (such as that from animals) had significantly poorer cognitive function compared to those who consumed the lowest amounts. Women who instead had a high intake of monounsaturated fats (such as olive oil) had better cognitive scores over time. Total fat, polyunsaturated fat, and trans fat, were not associated with cognitive performance.

The findings are consistent with research associating the Mediterranean diet (high in olive oil) with lower Alzheimer’s risk, and studies linking diets high in saturated fats with greater cognitive decline.

Recent posts at Mynd

A study involving 97 healthy older adults (65-89) has found that those with the “Alzheimer’s gene” (APOe4) who didn’t...

An Indian study involving 648 dementia patients, of whom 391 were bilingual, has found that, overall, bilingual patients developed dementia 4.5...

A study, involving 371 patients with mild cognitive impairment...

A study involving 206 spousal and adult children caregivers of dementia sufferers (mostly Alzheimer’s) has found that about 84% of...

A study involving 254 people with dementia living at home has found that 99% of people with dementia and 97% of their caregivers had one or more...

A new U.S. study suggests that Alzheimer's disease and other dementias are markedly under-reported on death certificates and medical records....

It’s often argued that telling people that they carry genes increasing their risk of Alzheimer’s will simply upset them to no purpose...

11 new genetic susceptibility factors for Alzheimer’s identified

The largest international study ever conducted on Alzheimer's...

Understanding a protein's role in familial Alzheimer's...

A brain imaging study of 162 healthy babies (2-25 months) has found that those who carried the ApoE4...

A gene linked to Alzheimer's has been linked to brain changes in childhood. This gene, SORL1, has two connections to Alzheimer’s: it...

Analysis of data from 237 patients with mild cognitive impairment...

Two studies indicate that young people carrying the “Alzheimer’s gene” (ApoE4...

Analysis of data from more than 8,000 people, most of them older than 60, has revealed that, among the 5,000 people initially tested cognitively...

Analysis of 700 subjects from the Alzheimer's Disease Neuroimaging Initiative has revealed a genetic mutation (rs4728029) that’s associated...

Analysis of brain scans and cognitive scores of 64 older adults from the NIA's Baltimore Longitudinal Study of Aging (average age 76) has found...