Drug derived from curcumin may help treat stroke

March, 2011

More evidence for the value of the curry spice curcumin comes from animal studies indicating a curcumin-derived drug may help treat stroke.

A new molecular compound derived from curcumin (found in turmeric) holds promise for treating brain damage caused by stroke. Turmeric has a long history of use in Ayurvedic and Chinese traditional medicine. However, curcumin has several important drawbacks as far as treating stroke is concerned — mainly because it can’t cross the blood-brain barrier. The new compound can.

In rabbit experiments, the drug was effective when administered up to an hour after stroke, which correlates with about three hours in humans. This is the same time frame for which tPA — the only drug currently approved for ischemic stroke — is currently approved.

The new drug is expected to move to human clinical trials soon.


Paul A. Lapchak presented these findings at the American Heart Association International Stroke Conference in Los Angeles on February. 9.

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