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Comparison of 17 people with severe obstructive sleep apnea (OSA) with 15 age-matched controls has revealed that those with OSA had reduced gray matter in several brain regions, most particularly in the left

The role of sleep in consolidating memory is now well-established, but recent research suggests that sleep also reorganizes memories, picking out the emotional details and reconfiguring the memories to help you produce new and creative ideas. In an experiment in which participants were shown scenes of negative or neutral objects at either 9am or 9pm and tested 12 hours later, those tested on the same day tended to forget the negative scenes entirely, while those who had a night’s sleep tended to remember the negative objects but not their neutral backgrounds.

No one is denying that boys are far more likely to be autistic than girls, but a new study has found that this perception of autism as a male disorder also means that girls are less likely to be diagnosed with autistic spectrum disorder (ASD) even when their symptoms are equally severe.

More evidence that vascular disease plays a crucial role in age-related cognitive impairment and Alzheimer’s comes from data from participants in the Alzheimer's Disease Neuroimaging Initiative.

A simple new cognitive assessment tool with only 16 items appears potentially useful for identifying problems in thinking, learning and memory among older adults. The Sweet 16 scale is scored from zero to 16 (with 16 representing the best score) and includes questions that address orientation (identification of person, place, time and situation), registration, digit spans (tests of verbal memory) and recall. The test requires no props (not even pencil and paper) and is easy to administer with a minimum of training. It only takes an average of 2 minutes to complete.

There have been mixed findings about the benefits of DHA (an omega-3 fatty acid), but in a study involving 485 older adults (55+) with age-related cognitive impairment, those randomly assigned to take DHA for six months improved the score on a visuospatial learning and episodic memory test. Higher levels of DHA in the blood correlated with better scores on the paired associate learning task.

A study involving young (average age 22) and older adults (average age 77) showed participants pictures of overlapping faces and places (houses and buildings) and asked them to identify the gender of the person. While the young adults showed activity in the brain region for processing faces (fusiform face area) but not in the brain region for processing places (

Do retired people tend to perform more poorly on cognitive tests than working people because you’re more likely to retire if your mental skills are starting to decline, or because retirement dulls the brain?

Carriers of the so-called ‘Alzheimer’s gene’ (apoE4) comprise 65% of all Alzheimer's cases. A new study helps us understand why that’s true.

Monitoring of 11 football players at a high school in Indiana, who wore helmets equipped with sensors that recorded impart, has revealed the problem of head injuries is deeper than was thought. Brain scans and cognitive tests, in addition to the impact data, found that some players who hadn't been diagnosed with concussions nevertheless had developed changes in brain function, correlated with cognitive impairment. The findings point to the dangers of repeated impact, regardless of whether consciousness is lost.

A Chinese study involving 153 older men (55+; average age 72), of whom 47 had mild cognitive impairment, has found that 10 of those in the MCI group developed probable Alzheimer's disease within a year.

A seven-year study involving 271 Finns aged 65-79 has revealed that increases in the level of

Following on from earlier studies that found individual neurons were associated with very specific memories (such as a particular person), new research has shown that we can actually regulate the activity of specific neurons, increasing the firing rate of some while decreasing the rate of others.

Data from 21,123 people, surveyed between 1978 and 1985 when in their 50s and tracked for dementia from 1994 to 2008, has revealed that those who smoked more than two packs per day in middle age had more than twice the risk of developing dementia, both Alzheimer's and

In a study involving 15 young adults, a very small electrical current delivered to the scalp above the right anterior

I love cognitive studies on bees. The whole notion that those teeny-tiny brains are capable of the navigation and communication feats bees demonstrate is so wonderful. Now a new study finds that, just like us, aging bees find it hard to remember the location of a new home.

Because people with damage to their

Following on from earlier research suggesting that simply talking helps keep your mind sharp at all ages, a new study involving 192 undergraduates indicates that the type of talking makes a difference.

An experiment with congenitally deaf cats has revealed how deaf or blind people might acquire other enhanced senses. The deaf cats showed only two specific enhanced visual abilities: visual localization in the peripheral field and visual motion detection. This was associated with the parts of the auditory cortex that would normally be used to pick up peripheral and moving sound (posterior auditory cortex for localization; dorsal auditory cortex for motion detection) being switched to processing this information for vision.

A study involving 48 adolescents, of whom 19 had been diagnosed with substance abuse/dependence, and 14 had a family history of substance abuse but no history of personal use, has found that greater alcohol use was associated with a significant decrease in attention and executive function (which is involved in planning and decision-making), while greater marijuana use was associated with poorer memory.

Data from 217 children from Inuit communities in Arctic Quebec (average age 11), of whom some had mothers that reported binge drinking during pregnancy, has revealed that the alcohol-exposed group, while similar to the control in accuracy and reaction time, showed a significant differences in their brains’ electrical activity while doing those tasks (a Go/No-go response inhibition task and a continuous recognition memory task).

A meta-analysis of 242 articles assessing the math skills of 1,286,350 people found no difference between the two sexes. This was confirmed in an analysis of the data from several large surveys of American adolescents (the National Longitudinal Surveys of Youth, the National Education Longitudinal Study of 1988, the Longitudinal Study of American Youth, and the National Assessment of Educational Progress).

A long-running study involving 299 older adults (average age 78) has found that those who walked at least 72 blocks during a week of recorded activity (around six to nine miles) had greater gray matter volume nine years later. Gray matter does shrink as we get older, so this is not about growth so much as counteracting decline. Walking more than 72 blocks didn’t appear to confer any additional benefit (in terms of gray matter volume).

We can see shapes and we can feel them, but we can’t hear a shape. However, in a dramatic demonstration of just how flexible our brain is, researchers have devised a way of coding spatial relations in terms of sound properties such as frequency, and trained blindfolded people to recognize shapes by their sounds. They could then match what they heard to shapes they felt. Furthermore, they were able to generalize from their training to novel shapes.

The issue of “mommy brain” is a complex one. Inconsistent research results make it clear that there is no simple answer to the question of whether or not pregnancy and infant care change women’s brains. But a new study adds to the picture.

In an experiment to investigate why testing might improve learning, 118 students were given 48 English-Swahili translation pairs. An initial study trialwas followed by three blocks of practice trials. For one group, the practice trial involved a cued recall test followed by restudy. For the other group, they weren’t tested, but were simply presented with the information again (restudy-only). On both study and restudy trials, participants created keywords to help them remember the association.

A study involving 48 healthy adults aged 18-39 has found that extraverts who were deprived of sleep for 22 hours after spending 12 hours in group activities performed worse on a vigilance task that did those extraverts who engaged in the same activities on their own in a private room. Introverts were relatively unaffected by the degree of prior social interaction.

Major surgery often produces cognitive dysfunction, usually temporary, but for some, long-lasting. It has been suggested that the problem might have to do with the immune system's inflammatory response. A new mouse study provides more evidence for this.

The study found that giving the mice a common inhibitor of the inflammatory response (anti-tumor necrosis factor (TNF) antibody), before orthopedic surgery, decreased postoperative cognitive decline. It’s hoped human clinical testing of this approach will begin within a year.

Beginning in 1971, healthy older adults in Gothenburg, Sweden, have been participating in a longitudinal study of their cognitive health. The first H70 study started in 1971 with 381 residents of Gothenburg who were 70 years old; a new one began in 2000 with 551 residents and is still ongoing. For the first cohort (born in 1901-02), low scores on non-memory tests turned out to be a good predictor of dementia; however, these tests were not predictive for the generation born in 1930.

Confirming earlier indications from small studies, a very large nationwide survey has found that people who have had cancer are 40% more likely to experience memory problems that interfere with daily functioning.

The U.S. study involved nearly 10,000 people aged 40 and older, of whom 1,305 (13.3%) reported they had cancer or a history of cancer. Of these, 14% answered yes to the question "Are you limited in any way because of difficulty remembering or because you experience periods of confusion?" Of those who did not have a history of cancer, 8% answered yes to this question.

Comparison of the brains of 22 smokers and 21 people who have never smoked in their lives has revealed that the left medial

Recent rodent studies add to our understanding of how estrogen affects learning and memory. A study found that adult female rats took significantly longer to learn a new association when they were in periods of their estrus cycle with high levels of estrogen, compared to their ability to learn when their estrogen level was low. The effect was not found among pre-pubertal rats. The study follows on from an earlier study using rats with their ovaries removed, whose learning was similarly affected when given high levels of estradiol.

Previous research has indicated that obesity in middle-age is linked to higher risk of cognitive decline and dementia in old age. Now a study of 32 middle-aged adults (40-60) has revealed that although obese, overweight and normal-weight participants all performed equally well on a difficult cognitive task (a

Inflammation in the brain appears to be a key contributor to age-related memory problems, and it may be that this has to do with the dysregulation of microglia that, previous research has shown, occurs with age.

A long-running study involving 1,157 healthy older adults (65+) who were scored on a 5-point scale according to how often they participated in mental activities such as listening to the radio, watching television, reading, playing games and going to a museum, has found that this score is correlated to the rate of cognitive decline in later years.

Confirming earlier research, a study involving 257 older adults (average age 75) has found that a two-minute questionnaire filled out by a close friend or family member is more accurate that standard cognitive tests in detecting early signs of Alzheimer’s.

The AD8 asks questions about changes in everyday activities:

A study involving 110 toddlers (aged 14-42 months), of whom 37 were diagnosed with an autism spectrum disorder and 22 with a developmental delay, has compared their behavior when watching a 1-minute movie depicting moving geometric patterns (a standard screen saver) on 1 side of a video monitor and children in high action, such as dancing or doing yoga, on the other.

Children with autism often focus intently on a single activity or feature of their environment. A study involving 17 autistic children (6-16 years) and 17 controls has compared brain activity as they watched a silent video of their choice while tones and vibrations were presented, separately and simultaneously.

When children learn to count, they do so by rote. Understanding what the numbers really mean comes later. This is reflected in the way children draw a number line. In the beginning, they typically put more space between the smaller numbers, with the larger numbers all scrunched up at the end (a logarithmic number line). Eventually they progress to a number line where the numbers are evenly spaced (linear number line).

Low levels of DHA, an omega-3 fatty acid, have been found in the brains of those with Alzheimer's disease, but the reason has not been known. A new study has found that lower levels of DHA in the liver (where most brain DHA is manufactured) were correlated with greater cognitive problems in the Alzheimer’s patients. Moreover, comparison of postmortem livers from Alzheimer’s patients and controls found reduced expression of a protein that converts a precursor acid into DHA, meaning the liver was less able to make DHA from food.

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