Adolescents with type 2 diabetes have diminished cognitive performance and brain abnormalities

September, 2010

Another study adds to growing evidence that diabetes, or poor glycaemic control, has serious implications for brain function.

A small study comparing 18 obese adolescents with type 2 diabetes and equally obese adolescents without diabetes or pre-diabetes has found that those with diabetes had significantly impaired cognitive performance, as well as clear abnormalities in the integrity of their white matter (specifically, reduced white matter volume, especially in the frontal lobe, as well as impaired integrity in both white and grey matter). Similar abnormalities have previously been found in adults with type 2 diabetes, but the subjects were elderly and, after many years of diabetes, generally had significant vascular disease. One study involving middle-aged diabetics found a reduction in the volume of the hippocampus, which was directly associated with poor glycaemic control.

It remains to be seen whether such changes can be reversed by exercise and diet interventions. While those with diabetes performed worse in all cognitive tasks tested, the differences were only significant for intellectual functioning, verbal memory and psychomotor efficiency.

Reference: 

Related News

Iron deficiency is the world's single most common nutrient deficiency, and a well-known cause of impaired cognitive, language, and motor development. Many countries therefore routinely supplement infant foods with iron.

Math-anxiety can greatly lower performance on math problems, but just because you suffer from math-anxiety doesn’t mean you’re necessarily going to perform badly.

IQ has long been considered to be a fixed attribute, stable across our lifetimes. But in recent years, this assumption has come under fire, with evidence of the positive and negative effects education and experiences can have on people’s performance.

In the study, 18 children (aged 7-8), 20 adolescents (13-14), and 20 young adults (20-29) were shown pictures and asked to decide whether it was a new picture or one they had seen earlier.

Brain imaging data from 103 healthy people aged 5-32, each of whom was scanned at least twice, has demonstrated that wiring to the

Binge drinking occurs most frequently among young people, and there has been concern that consequences will be especially severe if the brain is still developing, as it is in adolescence.

Most research into the importance of

Following animal research indicating that binge drinking damages the

Binge drinking is, unfortunately, most common among adolescents (12-20 years). But this is a time when brains are still developing. Does this make them more vulnerable to the detrimental effects of excessive alcohol?

An Australian study of 3796 14-year-olds has found that those who had been reported as having suffered abuse or neglect (7.9%) scored the equivalent of some three IQ points lower than those who had not been maltreated, after accounting for a large range of socioeconomic and other factors.

Pages

Subscribe to Latest newsSubscribe to Latest newsSubscribe to Latest health newsSubscribe to Latest news