Deep brain therapy effective in early Parkinson’s

03/2013

A 2-year trial involving 251 patients with Parkinson's disease and early motor complications (mean age, 52 years; mean duration of disease, 7.5 years) has found that those given deep brain stimulation surgery significantly improved their quality of life, motor disability, activities of daily living, levodopa-induced motor complications, and time with good mobility and no dyskinesia. Those given normal medical therapy, on the other hand, declined or at best got no worse. Serious adverse events related to surgical implantation or the neurostimulation device occurred in 18% of patients.

“The study has confirmed the best medical practice for a person with Parkinson’s disease is to perform DBS surgery around 4 to 7 years into the condition, as opposed to waiting until the medications stop working.”

http://www.futurity.org/health-medicine/deep-brain-therapy-effective-in-early-parkinsons/

[3321] Schuepbach, W. M. M., Rau J., Knudsen K., Volkmann J., Krack P., Timmermann L., et al.
(2013).  Neurostimulation for Parkinson's Disease with Early Motor Complications.
New England Journal of Medicine. 368(7), 610 - 622.

Related News

A study involving 2,050 people aged 70 to 89 has found that mild cognitive impairment was 1.5 times more common in men than women.

Reports on cognitive decline with age have, over the years, come out with two general findings: older adults do significantly worse than younger adults; older adults are just as good as younger adults.

A pilot study involving six patients with mild Alzheimer’s has shown using Deep Brain Stimulation (DBS) is safe and may help improve memory, or at least slow decline. Patients received continuous stimulation for 12 months, between 2005 and 2008.

Following on from indications that gum disease might be a risk factor for dementia, analysis of data from 152 subjects in the Danish Glostrop Aging Study has revealed that periodontal inflammation at age 70 was strongly associated with lower cognitive scores (on the Digit Symbol Test).

A two-year study involving 271 older adults (70+) with mild cognitive impairment has found that the rate of brain atrophy in those taking folic acid (0.8 mg/d), vitamin B12 (0.5 mg/d) and vitamin B6 (20 mg/d), was significantly slower than in those taking a placebo, with those taking the supplem

A number of studies have found evidence that fruits and vegetables help fight age-related cognitive decline, and this has been thought to be due to their antioxidant and anti-inflammatory effects.

I have often spoken of the mantra: What’s good for your heart is good for your brain.

A number of studies have found that source memory (knowing where you heard/read/experienced something) is a particular problem for older adults. Destination memory (knowing who you’ve told) is an area that has been much less studied.

On the subject of the benefits of walking for seniors, it’s intriguing to note a recent pilot study that found frail seniors who walked slowly (no faster than one meter per second) benefited from a brain fitness program known as Mindfit.

A study involving 65 older adults (59-80), who were very sedentary before the study (reporting less than two episodes of physical activity lasting 30 minutes or more in the previous six months), has found that those who joined a walking group improved their cognitive performance and the connecti

Pages

Subscribe to Latest newsSubscribe to Latest newsSubscribe to Latest health newsSubscribe to Latest news