A year-long study involving 424 sedentary, mobility-limited seniors aged 70-89, has found that variants in a specific gene (the ACE I/D gene) affect seniors’ ability to benefit from exercise. Physical activity intervention led to greater improvements in walking speed among ID and DD genotype carriers (29.9% and 13.7% respectively), but among II genotype carriers, health education alone led to more improvements in walking speed than physical activity intervention (20% vs. 18.5%).
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