New findings identify a mechanism that accelerates aging in the brain and gives rise to Alzheimer's disease.
Alzheimer's & Other Dementias
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Aging linked to impaired garbage collection in the brain |
Link found between chronic inflammation and Alzheimer's gene risk |
Alzheimer's gene linked to damage to brain connectionsA study has found that synapses in people who had died with Alzheimer's contained clumps of clusterin and clumps of amyloid beta. These protein clumps may be damaging the links between neurons. |
A study involving 4,050 people with late-onset Alzheimer's disease (mean age 80) has classified them into six groups based on their cognitive functioning at the time of diagnosis. A genetic study found two of the groups showed strong genetic associations. |
Five new risk genes for Alzheimer's diseaseGenetic data from more than 94,000 individuals has revealed five new risk genes for Alzheimer's disease, and confirmed 20 known others. The new genes are: IQCK, ACE, ADAM10, ADAMTS1 and WWOX. |
Alzheimer's gene affects IQ from childhoodAnalysis of some old longitudinal studies has found that those carrying the APOE4 gene scored lower on IQ tests during childhood and adolescence. The effect was much stronger in girls than in boys, and affected reasoning most strongly. |
Poor sleep has been associated with the development of Alzheimer's disease, and this has been thought to be in part because the protein amyloid beta increases with sleep deprivation. A new study explains more. |