Genetic data from more than 94,000 individuals has revealed five new risk genes for Alzheimer's disease, and confirmed 20 known others. The new genes are: IQCK, ACE, ADAM10, ADAMTS1 and WWOX.
Accumulating evidence suggests that tau spreads through brain tissue like an infection, traveling from
Analysis of some old longitudinal studies has found that those carrying the APOE4 gene scored lower on IQ tests during childhood and adolescence. The effect was much stronger in girls than in boys, and affected reasoning most strongly.
Data from a ten-year study involving 345 Alzheimer's patients has found that
Poor sleep has been associated with the development of Alzheimer's disease, and this has been thought to be in part because the protein amyloid beta increases with sleep deprivation. A new study explains more.
A small study has found that a 12-week exercise program significantly improved cognition in both older adults with
A Japanese study looking at 128 patients' fecal samples, found that fecal concentrations of ammonia, indole, skatole and phenol were higher in dementia patients compared to those without dementia, while levels of beneficial Bacteroides were lower in dementia patients.
A clinical trial involving 9361 older adults (50+) with hypertension but without diabetes or history of stroke has found that intensive control of blood pressure significantly reduced the risk of developing mild cognitive impairment.
Survey data from 6,807 Danish older adults (average age 60) in the Copenhagen City Heart Study, has found that being distressed in late midlife is associated with a higher risk of dementia in later life.
Poor sleep has been associated with Alzheimer's disease risk, but a new study suggests a specific aspect of sleep is important.