Alzheimer's & Other Dementias

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A study using two training programs to help dementia patients regain eating skills, found spaced retrieval training was particularly effective.

Loss of memory and problems with judgment in dementia patients can cause difficulties in relation to eating and nutrition; these problems in turn can lead to poor quality of life, pressure ulcers and infections.

  • A clinical trial has found improvement in verbal (but not general) memory in patients with mild Alzheimer's who drank a nutritional cocktail for 12 weeks.

A European trial involving 225 patients with mild Alzheimer's has found that those who drank Souvenaid (a cocktail of uridine, choline and the omega-3 fatty acid DHA, plus B vitamins, phosopholipids and antioxidants) for 12 weeks were more likely to improve their performance in a delayed verbal

Healthy older adults reporting subjective cognitive impairment are dramatically more likely to progress to MCI or dementia, and decline significantly faster.

Subjective cognitive impairment (SCI), marked by situations such as when a person recognizes they can't remember a name like they used to or where they recently placed important objects the way they used to, is experienced by between one-quarter and one-half of the population over the age of 65.

Two large studies have found moderate exercise was associated with a lower risk of developing mild cognitive impairment. A small study suggests women may benefit more than men.

A German study involving nearly 4000 older adults (55+) has found that physical activity significantly reduced the risk of developing mild cognitive impairment over a two-year period.

A mouse study found Rapamycin improved learning and memory and reduced Alzheimer's-like damage in the brain.

Evidence that levels of damaged tau protein in the cerebrospinal fluid is associated with atrophy in the medial temporal lobe may help diagnose Alzheimer’s early.

A study involving 57 cognitively healthy older adults has found that those who showed decreased memory performance two years later (20 of the 57) had higher baseline levels of phosphorylated tau231 in the

A large five-year study concludes that late-life hypertension doubles the risk of dementia in those with executive dysfunction only (but not for those with memory dysfunction alone or memory and executive dysfunction).

Midlife hypertension has been confirmed as a risk factor for the development of dementia in late life, but there have been conflicting findings about the role of late-life hypertension.

A 15-year study concludes that a simple progression rate calculated at the initial visit can reliably identify slow, intermediate and rapid progression.

By following 597 Alzheimer’s patients over 15 years, researchers have determined that a simple progression rate can be calculated at the initial visit, using symptom onset and present performance, and that this can reliably identify slow, intermediate and rapid progression.

A comprehensive survey confirms the value of an early diagnostic tool, and provides strong evidence for the central importance of amyloid-beta protein plaques in the development of Alzheimer’s.

A survey of more than 100 studies involving PIB-PET, a diagnostic tool that involves injecting a radiotracer called

Data from The 90+ Study has revealed a sharply increasing incidence rate for dementia, from nearly 13% per year for 90-94, to over 40% in the 100+ age group.

Data from 330 participants in The 90+ Study, of whom 70% were women, has revealed an overall annual incidence rate of 18.2% for dementia, rising from 12.7% per year in the 90-94 age group, to 21.2% in the 95-99 age group and 40.7% per year in the 100+ age group.

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